As a technique for studying biomolecular binding, surface plasmon resonance has been shown to be of great value in a diverse range of research activities including drug discovery, cell signaling, gene regulation, and structure-function studies.

Some of the different types of affinity pairs to be characterized by this technique include:

• Protein-Protein
• Protein-DNA
• Protein-Small Molecule
• Antibody-Antigen
• Membrane Receptor-Ligand
• Peptide-Receptor.

Kinetics of association and dissociation, affinity constant measurements, concentration determinations and ligand fishing are all examples of the capabilities inherent in SPR and SensiQ provides this valuable data in an easy to use, affordable instrument

Antibody Characterization

Characterizing the affinity profile of antibody interactions provides significant information in applications such as:

• Biotherapeutic Research
• Antibody Assay Kit Development
• Antibody QC
• Bioprocessing

Small Molecule Interactions

Interactions involving small molecules are the basis of drug development research. The high sensitivity of SensiQ Pioneer coupled with novel surface chemistries allow researchers to perform kinetics measurements on molecules smaller than 150 Da, enabling improved information about new drug candidates.

Protein-Protein Interaction Kinetics

Understanding the kinetics of protein interactions furthers research in areas such as:

• Cell Signaling
• Disease Mechanism Studies
• Biomarker Development
• Structure-Function Analysis